Thelargeinter-patientvariabilityinresponsestodrugsresultsfromtwomainsources:1.Pharmacokineticsvariabilityinabsorption,distribution,metabolismorelimination2.Pharmacodynamicsvariabilityinsensitivityatorbeyondreceptors,duetoacquireddifferences(e.g.age,obesit (共 8638 字) [阅读本文] >>